To unravel the complexities of biological phenomena, scientists have long relied on microscopy to visualize the intricate details of their specimens, including tissue architecture, cell morphology, ...

It has been over a decade since super-resolution microscopy was awarded the 2014 Nobel Prize in Chemistry, and after tremendous advancements over the years, it is on its way to becoming a standard ...

There is a growing demand for non-invasive insights into the complex three-dimensional subcellular dynamics within living tissues on the frontier of biological research. To achieve simultaneous ...

Even those who maintain that super-resolution microscopy is a powerful tool of biological discovery have admitted that it may have a bit of an image problem. For example, in a recent review, several ...

Existing super-resolution techniques still face considerable challenges in complex deep tissue environments. For example, Stimulated Emission Depletion (STED) microscopy relies on a doughnut-shaped ...

Structured illumination microscopy (SIM) is the most preferable system for live-cell super-resolution imaging. It enables the observation of intricate subcellular dynamics. However, conventional SIM ...

When single-molecule super-resolution microscopes were first commercialized some 15 years ago, they made headlines for their ability to resolve individual molecules and structures at the nanometer ...

Advanced light microscopy techniques are giving scientists a new understanding of human biology and what goes wrong in diseases Katarina Zimmer, Knowable Magazine Innovative techniques are helping ...

Researchers have discovered a groundbreaking use of terahertz (THz) imaging to visualize cochlear structures in mice, offering non-invasive, high-resolution diagnostics. By creating 3D reconstructions ...

A new publication from Opto-Electronic Advances; DOI 10.29026/oea.2024.240035 discusses multiplexed stimulated emission depletion nanoscopy for multi-color live-cell long-term imaging. In the field of ...

A new study shows how the single-molecule organization of receptors in a cellular context determines the function of antibodies, opening up new pathways for the development of cancer immunotherapies.